Mouse Strain information
APB ID 4915
Added 16/10/2009
Last Edited 17/05/2014
Strain nomenclature: BALB/c-IL13tm2Anjm IL4ratm1Sz/AnuApb
Nickname: IL-13 -/- IL-4Ra -/-
Genetics
Strain Types Mutant strain
Genetic Details Targeted knockout
Mode of Inheritance Recessive
1.  Affected Gene Name: interleukin 13  
Chromosome 11
Affected Gene Symbol Il13
Protein expression of altered gene: Nil
Genetic alteration of gene: A neomycin cassette was inserted into exon 3.
Location on chromosome (bp): 53444826-53448204 bp, - strand (From VEGA annotation of NCBI Build 37)
MGI Gene Accession ID

Please also use this link to determine if other mutants have been registered with MGI (Mouse Genome Informatics)

 MGI:96541
Synonyms Il-13
Allele Name targeted mutation 2, Andrew NJ McKenzie
Allele Symbol Il13tm2Anjm
MGI Allele Accession ID MGI:1931804
Allele synonyms: IL-13KO, IL13-
2.  Affected Gene Name: interleukin 4 receptor, alpha  
Chromosome 7
Affected Gene Symbol Il4ra
Protein expression of altered gene: Unknown
Genetic alteration of gene: A neomycin resistance cassette replaced exons 7 - 9 of the gene.
MGI Gene Accession ID

Please also use this link to determine if other mutants have been registered with MGI (Mouse Genome Informatics)

 MGI:105367
Synonyms D124, IL-4 receptor alpha chain, Il4r
Allele Name targeted mutation 1, Leonard Shultz
Allele Symbol Il4ratm1Sz
MGI Allele Accession ID MGI:1861951
Allele synonyms: IL-4R KO, IL-4R-, IL-4Ralpha-, Il-4ralphatm1Sz
Mutant Construction Technique None
Phenotype
Phenotype Homozygous State Unknown
Original Genetic Background 129
Genetic Background Currently Maintained BALB/c
Strain identification
How is this strain characterised? Genotyping
PCR protocols IL13_IL4rMultiplex
Fertility and Strain maintenance
Fertility and Strain maintenance
Relevant bibliographic / database references
Strain Specific References
Other Related References
General information
Associated IP rights? Unknown
Does it Model a Human Condition? Unknown
Applicable Research Areas Immunology and inflammation
Keywords
  • interleukin
  • IL10
  • IL5
  • Th2
  • T cell
  • parasite
Is the strain available in any form to other researchers Yes
APB stock stored as: Cryopreserved sperm (from 10 mice)

APB stock genotyped verified by: Unverified
Are live mice available? No
MTA needs to be signed? Yes


     

 


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