Mouse Strain information
APB ID 5249
Added 20/10/2010
Last Edited 09/12/2019
Strain nomenclature: C57BL/6-Tg(FXN/EGFP)CSars/Apb
Nickname: FGFPC
Strain designation name: C57BL/6-Tg(FXN/EGFP)CSars/Apb
Genetics
Strain Types Mutant strain
Inbred
Genetic Details Transgenic: BAC
Mode of Inheritance Recessive
1.   Transgene: Human FRATAXIN gene  
Mutant Construction Technique None
Phenotype
Phenotype Homozygous State Normal
Phenotype Heterozygous State Normal
Original Genetic Background C57BL/6
Genetic Background Currently Maintained C57BL/6
Coat Colour Black
Strain identification
How is this strain characterised? Genotyping
Fertility and Strain maintenance
Fertility and Strain maintenance
Relevant bibliographic / database references
Strain Specific References
Other Related References
General information
Associated IP rights? Unknown
Does it Model a Human Condition? Yes
Description of human condition: Friedreich ataxia
Applicable Research Areas Developmental biology
Research tools
Models for human disease
Neurobiology
Keywords
  • Friedreich ataxia
  • neurodegenerative disease
  • GAA repeat expansion
  • iron-sulfur clusters
Is the strain available in any form to other researchers Yes
APB stock stored as: Cryopreserved sperm (from 5 mice)
Are live mice available? Unknown
MTA needs to be signed? Yes


     

 


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