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Mouse Strain information

APB ID

6803

Added

23/01/2012

Last Edited

16/12/2022

Strain nomenclature:

C57BL/6N-Csf3rtm1(KOMP)Vlcg/Marp

Nickname:

APN 183

Genetics

Strain Types

Mutant strain

Genetic Details

Targeted knockout

ES Cell-Line Used

ES cell clone ID: 13448A-B8

Mode of Inheritance

Recessive

1. Affected Gene Name: colony stimulating factor 3 receptor (granulocyte)

Chromosome	4
Affected Gene Symbol	Csf3r
Protein expression of altered gene:	Unknown
Genetic alteration of gene:	The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 16554bp between positions 125704584-125721137 of Chromosome 4 (Genome Build37). (J:136110)
Location on chromosome (bp):	Chr4:125701794-125721684 bp, + strand
MGI Gene Accession ID Please also use this link to determine if other mutants have been registered with MGI (Mouse Genome Informatics)	MGI:1339755
Allele Name	colony stimulating factor 3 receptor (granulocyte); targeted mutation 1, Velocigene
Allele Symbol	Csf3rtm1(KOMP)Vlcg
MGI Allele Accession ID	MGI:4452883

Point mutation sequence:

Insertion/Tagging details:

Guide(s) RNA sequence:

Mutant Construction Technique

None

Phenotype

Phenotype Homozygous State

Unknown - Not bred to homozygocity

Phenotype Heterozygous State

Normal

Original Genetic Background

C57Bl/6NTac, VGB6

Genetic Background Currently Maintained

C57BL/6N

Coat Colour

Black

Eye Colour

Brown

Strain identification

How is this strain characterised?

Genotyping

Fertility and Strain maintenance

Fertility and Strain maintenance

Relevant bibliographic / database references

General information

Other Patent Technologies?

Associated IP rights?

Unknown

Does it Model a Human Condition?

Unknown

Research value of this Strain

Imported from Knockout Mouse Project Repository (KOMP).

Keywords

ES cell

Is the strain available in any form to other researchers

Yes

APB stock stored as:

Cryopreserved sperm (from 5 mice)

Are live mice available?

MTA needs to be signed?

Yes