Mouse Strain information
APB ID 8315
Added 02/10/2017
Last Edited 21/01/2025
Strain nomenclature: C57BL/6-Slc2a12tm1loxpRog
Nickname: GLUT12 KO
Genetics
Strain Types Mutant strain
Genetic Details Targeted knockout
Mode of Inheritance Recessive
1.  Affected Gene Name: solute carrier family 2 (facilitated glucose transporter), member 12  
Chromosome 10
Affected Gene Symbol Slc2a12
Genetic alteration of gene: Exon 2 flanked by LoxP sites, crossed with Cre strain deleted exon 2.
Location on chromosome (bp): 22645011-22704285 bp, + strand (From VEGA annotation of GRCm38)
MGI Gene Accession ID

Please also use this link to determine if other mutants have been registered with MGI (Mouse Genome Informatics)

MGI:3052471
Synonyms Glut12, GLUT-12
Allele Symbol Slc2a12tm1loxpRog
Ensembl Gene ID: ENSMUSG00000037490
Point mutation sequence:
Insertion/Tagging details:
Guide(s) RNA sequence:
Mutant Construction Technique None
Phenotype
Phenotype Homozygous State Glucose intolerant Insulin intolerant Insulin Resistance
Phenotype Heterozygous State Normal
Genetic Background Currently Maintained C57BL/6
Coat Colour Black
Strain identification
How is this strain characterised? Genotyping
Fertility and Strain maintenance
Fertility and Strain maintenance
Relevant bibliographic / database references
General information
Associated IP rights? Unknown
Does it Model a Human Condition? Unknown
Applicable Research Areas Diabetes
Keywords
  • Glucose
Is the strain available in any form to other researchers Yes
APB stock stored as: Cryopreserved sperm (from 10 mice)
Are live mice available? No
MTA needs to be signed? Yes


     

 


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