Mouse Strain information
APB ID 8579
Added 02/10/2018
Last Edited 10/12/2024
Strain nomenclature: C57BL/6-Tnfsf12tm1/Apb
Nickname: Tweak KO/C57BL/6
Genetics
Strain Types Mutant strain
Genetic Details Targeted knockout
Mode of Inheritance Recessive
1.  Affected Gene Name: tumor necrosis factor (ligand) superfamily, member 12  
Chromosome 11
Affected Gene Symbol Tnfsf12
Location on chromosome (bp): 69686250-69695849 bp, - strand (From VEGA annotation of GRCm38)
MGI Gene Accession ID

Please also use this link to determine if other mutants have been registered with MGI (Mouse Genome Informatics)

MGI:1196259
Synonyms APO3L, DR3L, Tweak
Point mutation sequence:
Insertion/Tagging details:
Guide(s) RNA sequence:
Mutant Construction Technique None
Phenotype
Phenotype Homozygous State Normal
Phenotype Heterozygous State Normal
Genetic Background Currently Maintained C57BL/6
Coat Colour Black
Strain identification
How is this strain characterised? Genotyping
Fertility and Strain maintenance
Fertility and Strain maintenance
Relevant bibliographic / database references
General information
Associated IP rights? Unknown
Does it Model a Human Condition? Unknown
Applicable Research Areas Immunology and inflammation
Haematology
Is the strain available in any form to other researchers Yes
APB stock stored as: Cryopreserved sperm (from 5 mice)
Are live mice available? Unknown
MTA needs to be signed? Yes


     

 


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