Mouse Strain information
APB ID 88
Added 06/02/2006
Last Edited 10/05/2014
Strain nomenclature: C57BL/6JSfdAnu-Kcnv1vibe/AnuApb
Nickname: Vibes
Strain designation name: C57BL/6JSfdAnu-Kcnv1vibe/AnuApb
Genetics
Strain Types Mutant strain
Genetic Details Chemically induced : ENU
Mode of Inheritance Recessive
1.  Affected Gene Name: potassium channel, subfamily V, member 1  
Chromosome 15
Affected Gene Symbol Kcnv1
Protein expression of altered gene: Nil
Genetic alteration of gene: ENU induced mutation in 3' UTR.
Location on chromosome (bp): 44937830-44946373 bp, - strand (From NCBI annotation of NCBI Build 37)
MGI Gene Accession ID

Please also use this link to determine if other mutants have been registered with MGI (Mouse Genome Informatics)

 MGI:1914748
Allele Name vibes
Allele Symbol Kcnv1vibe
MGI Allele Accession ID MGI:3614803
Ensembl Gene ID: ENSMUSG00000022342
Transcript ID: ENSMUST00000022967
Transcript name: Kcnv1-201
bp change: T to C at position 2612 on cDNA
Exon number: 3
Exon ID: ENSMUSE00000258359
cDNA position: 2612
Version: NCBI m37, Ensembl build 55
Mutant Construction Technique None
Phenotype
Phenotype Homozygous State Tetanic ataxia at weaning, shaking. Video available. Please contact APB Curator for the video. It is too large to post here.
Original Genetic Background C57BL/6JSfdAnu
Genetic Background Currently Maintained C57BL/6JSfdAnu
Strain identification
How is this strain characterised? Genotyping
PCR protocols Vibes A –D15Mit229 (18cM)
Vibes B –D15Mit86 (18cM)
Vibes (Amplifluor)
Fertility and Strain maintenance
Fertility and Strain maintenance
Relevant bibliographic / database references
General information
Associated IP rights? No
Does it Model a Human Condition? Unknown
Applicable Research Areas Neurobiology
Keywords
  • Ataxia
  • Shaking
  • Weakness
  • ENU
Is the strain available in any form to other researchers Yes
APB stock stored as: Cryopreserved sperm (from 11 mice)

APB stock genotyped verified by: The APF
Are live mice available? No
MTA needs to be signed? Yes


     

 


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