Home - Australian Phenome Bank

Mouse Strain information

APB ID

9116

Added

11/01/2021

Last Edited

21/06/2023

Strain nomenclature:

C57Bl/6-Myl9tm1c(KOMP)Wtsi/AnuApb

Nickname:

Myl9 fl/fl

Genetics

Strain Types

Inbred

Genetic Details

ES cells targeting (Homologous recombination)

Mode of Inheritance

Semi-dominant

1. Affected Gene Name: myosin, light polypeptide 9, regulatory

Chromosome	2
Affected Gene Symbol	Myl9
Genetic alteration of gene:	LoxP sites flanking Exon 3 and 4. ? Targeted ES cells with Myl9tm1b(KOMP)Wtsi allele originally obtained from KOMP (now MMRRC). Microinjection and germline transmission was performed at the APN Monash node. Following germline transmission, mice were bred with a Flpe line to remove the LacZ-neo cassette, leaving only the LoxP-flanked allele.
Location on chromosome (bp):	156617340-156623578 bp
MGI Gene Accession ID Please also use this link to determine if other mutants have been registered with MGI (Mouse Genome Informatics)	MGI:2138915
Allele Name	myosin, light polypeptide 9, regulatory; targeted mutation 1c, Wellcome Trust Sanger Institute
Allele Symbol	Myl9tm1c(KOMP)Wtsi

Point mutation sequence:

Insertion/Tagging details:

Guide(s) RNA sequence:

Mutant Construction Technique

None

Phenotype

Phenotype Homozygous State

Wildtype

Phenotype Heterozygous State

Wildtype

Genetic Background Currently Maintained

C57BL/6

Strain identification

Fertility and Strain maintenance

Fertility and Strain maintenance

Relevant bibliographic / database references

General information

Associated IP rights?

Unknown

Does it Model a Human Condition?

Unknown

Is the strain available in any form to other researchers

Possibly

APB stock stored as:

Cryopreserved sperm (from 5 mice)

Are live mice available?

Unknown

MTA needs to be signed?

Yes